The genetics of systemic lupus erythematosus: differences across ethnicities

Genetics of systemic lupus erythematosus

Neurobrucellosis in systemic lupus erythematosus

Background: Brucellosis is a zoonotic infection which is endemic in many countries. It is a multisystem disease which may present with a broad spectrum of clinical manifestations and complications. Neurobrucellosis is an uncommon complication of brucellosis. Case presentation: A 25-year-old woman with a history of lupus for 5 months referred to the emergency ward of Shahid Beheshti Hosp...

Systemic lupus erythematosus in Arab children. Differences and similarities with different ethnicities.

OBJECTIVE To describe systemic lupus erythematosus (SLE) features among Arab children, and compare with cohorts from different ethnicities. METHODS This retrospective analysis of all published English literature on SLE in Arab children was conducted in March 2013. The percentage and frequencies of the clinical and laboratory features were collected, and compared between different Arab countri...

Genetics and Epigenetic in Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) (OMIM #152700) is the prototype of a multiorgan autoimmune disease and still considered as a disease with an ambiguous etiology. The disease predominantly affects women during the reproductive years at a ratio of eight women per one man (Lopez, 2003). Its pathogenesis is multifactorial lying on genetic and environmental factors in which it occurs in geneticall...

Systemic lupus erythematosus genetics: what’s new?

Benjamin Rhodes & Timothy J Vyse† †Author for correspondence Imperial College London, Section of Molecular Genetics and Rheumatology, Faculty of Medicine, Du Cane Road, London, W12 0NN, UK Tel.: +44 208 383 2339; Fax: +44 208 383 2379; [email protected] ‘Identifying SLE susceptibility genes is important because they will highlight pathways fundamental to the development of SLE, and may, in ...